Week 11 · College Football

USC vs Indiana prediction

The TailgateNinjas model gives Indiana a 75% chance to beat USC in this College Football matchup. Updated August 29, 2026.

#8 Big Ten Conference

USC

31% to make the 12

@

#4 Big Ten Conference

Indiana

63% to make the 12

The model's read

SpreadIndiana −10.5Vegas
Projected scoreUSC 21 — Indiana 31

Indiana should handle it: 10.5-point edge, 75% to win.

Chaos meter50 · LEAN
50/ 100
CalmMayhem

USC

25%

to win

Indiana

75%

to win

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Tale of the tape

2025 efficiency · ranks
USC
vs
Indiana
#4Offense · EPA/play#5
#65Defense · EPA/play#7
#21Explosiveness#74
#8Success rate#3
37%Returning production25%

National ranks from last season (1 = best). The 2026 outlook builds on this.

Series history

4 meetings all-time

USC leads 4–0

Last met 1982 · USC 28–7 Indiana— USC won

Both sidelines

via Google News

What USC is hearing

What Indiana is hearing

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