Week 7 · College Football

Louisville vs Syracuse prediction

The TailgateNinjas model gives Louisville a 66% chance to beat Syracuse in this College Football matchup. Updated August 29, 2026.

#39 Atlantic Coast Conference

Louisville

13% to make the 12

@

#90 Atlantic Coast Conference

Syracuse

2% to make the 12

The model's read

SpreadLouisville −6.5Model
Projected scoreLouisville 29 — Syracuse 23

Louisville is the pick by 6.5, but it's live — 66% on the model.

Chaos meter67 · LIVE
67/ 100
CalmMayhem

Louisville

66%

to win

Syracuse

34%

to win

Who wins?

Be the first

Tap a team to call it — then see if the crowd agrees with the model.

Think you know better?

Pick this game against the spread

Make your pick →

Tale of the tape

2025 efficiency · ranks
Louisville
vs
Syracuse
#82Offense · EPA/play#123
#21Defense · EPA/play#129
#97Explosiveness#109
#37Success rate#111
46%Returning production14%

National ranks from last season (1 = best). The 2026 outlook builds on this.

Series history

21 meetings all-time

Louisville leads 13–8

Last met 2022 · Syracuse 31–7 Louisville— Syracuse won

Both sidelines

via Google News

What Louisville is hearing

What Syracuse is hearing

Get The Drop

One email on Tuesdays: the week's biggest swings, and a straight accounting of the calls we missed.

No spam, no selling your address. One click to leave.