Week 15 · NFL
San Francisco 49ers vs Los Angeles Chargers prediction
The TailgateNinjas model gives Los Angeles Chargers a 51% chance to beat San Francisco 49ers in this NFL matchup. Updated August 4, 2026.
#6 NFC West
San Francisco 49ers
70% to make the playoffs
#11 AFC West
Los Angeles Chargers
67% to make the playoffs
The model's read
A coin flip. The model nudges Los Angeles Chargers by a field goal — 51% to win.
San Francisco 49ers
49%
to win
Los Angeles Chargers
51%
to win
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Tale of the tape
2025 efficiency · ranksSan Francisco 49ersLos Angeles ChargersNational ranks from last season (1 = best). The 2026 outlook builds on this.
Series history
7 meetings since 1999Los Angeles Chargers leads 5–2
Last met 2022 · San Francisco 49ers 22–16 Los Angeles Chargers— San Francisco 49ers won
Both sidelines
via Google NewsWhat San Francisco 49ers is hearing
What Los Angeles Chargers is hearing
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