Week 2 · NFL

Indianapolis Colts vs Kansas City Chiefs prediction

The TailgateNinjas model gives Kansas City Chiefs a 68% chance to beat Indianapolis Colts in this NFL matchup. Updated August 4, 2026.

#24 AFC South

Indianapolis Colts

23% to make the playoffs

@

#8 AFC West

Kansas City Chiefs

80% to make the playoffs

The model's read

SpreadKansas City Chiefs −6.5Vegas
Projected scoreIndianapolis Colts 19Kansas City Chiefs 25

Kansas City Chiefs is the pick by 6.5, but it's live — 68% on the model.

Chaos meter63 · LIVE
63/ 100
CalmMayhem

Indianapolis Colts

32%

to win

Kansas City Chiefs

68%

to win

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Tale of the tape

2025 efficiency · ranks
Indianapolis Colts
vs
Kansas City Chiefs
#9Offense · EPA/play#11
#16Defense · EPA/play#12
#8Success rate#14

National ranks from last season (1 = best). The 2026 outlook builds on this.

Series history

17 meetings since 1999

Indianapolis Colts leads 12–5

Last met 2025 · Kansas City Chiefs 2320 Indianapolis ColtsKansas City Chiefs won

Both sidelines

via Google News

What Indianapolis Colts is hearing

What Kansas City Chiefs is hearing

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