Week 3 · NFL

Los Angeles Chargers vs Buffalo Bills prediction

The TailgateNinjas model gives Buffalo Bills a 60% chance to beat Los Angeles Chargers in this NFL matchup. Updated August 4, 2026.

#11 AFC West

Los Angeles Chargers

67% to make the playoffs

@

#5 AFC East

Buffalo Bills

85% to make the playoffs

The model's read

SpreadBuffalo Bills −3.5Vegas
Projected scoreLos Angeles Chargers 20Buffalo Bills 24

A coin flip. The model nudges Buffalo Bills by a field goal — 60% to win.

Chaos meter80 · TOSS-UP
80/ 100
CalmMayhem

Los Angeles Chargers

40%

to win

Buffalo Bills

60%

to win

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Tale of the tape

2025 efficiency · ranks
Los Angeles Chargers
vs
Buffalo Bills
#25Offense · EPA/play#3
#7Defense · EPA/play#13
#19Success rate#2

National ranks from last season (1 = best). The 2026 outlook builds on this.

Series history

12 meetings since 1999

Los Angeles Chargers leads 7–5

Last met 2023 · Los Angeles Chargers 2224 Buffalo BillsBuffalo Bills won

Both sidelines

via Google News

What Los Angeles Chargers is hearing

What Buffalo Bills is hearing

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