Week 5 · NFL

Detroit Lions vs Arizona Cardinals prediction

The TailgateNinjas model gives Detroit Lions a 74% chance to beat Arizona Cardinals in this NFL matchup. Updated August 4, 2026.

#9 NFC North

Detroit Lions

69% to make the playoffs

@

#31 NFC West

Arizona Cardinals

0% to make the playoffs

The model's read

SpreadDetroit Lions −8.5Vegas
Projected scoreDetroit Lions 26Arizona Cardinals 18

Detroit Lions is the pick by 8.5, but it's live — 74% on the model.

Chaos meter53 · LIVE
53/ 100
CalmMayhem

Detroit Lions

74%

to win

Arizona Cardinals

26%

to win

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Tale of the tape

2025 efficiency · ranks
Detroit Lions
vs
Arizona Cardinals
#7Offense · EPA/play#23
#14Defense · EPA/play#27
#12Success rate#22

National ranks from last season (1 = best). The 2026 outlook builds on this.

Series history

19 meetings since 1999

Arizona Cardinals leads 10–8–1

Last met 2024 · Arizona Cardinals 1320 Detroit LionsDetroit Lions won

Both sidelines

via Google News

What Detroit Lions is hearing

What Arizona Cardinals is hearing

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